Organic metallo mercapto sulphonic compound and process of making same



Patented Eco. 9, 193% UNITED STATES hltdgldl PATENT QFFICE VTALTER SCI-IOELLER, ERIGH :sonewaanr, AND ADOLF manor, or BERLIN, GER-MANY, ASSIGNORS TO CHEMISGHE FABBIK ans Aorinn (VORM. n. SGHERING-J, or BERLIN,

GERMANY, A FIRM ORGANIC METALLO MERCAPTO SULPHONIC C OMPOUND AND PROCESS OF MAKING SAME No Drawing. Application filed April 26, 1927, Serial No. 186,815, and. in Germany May 5, 19526.

Our invention refers to the production of organic metallo mercaptosulphonic com-- pounds which corresponds to the formula X- (NH-CH -SO Na) (S-Me)- son 7 being also nonpoisonous.

The new compounds are slightly yellow colored substances which dissolve very readily in water and can be precipitated from such solutions by alcohol or methyl alcohol.

The invention is illustrated in the following examples, the parts being by weight.

Ewample I 37,6 parts ,B-aminox-auromercapto ethane sulphonic sodium (obtainablefrom ,8-aminou-chlorethane sulphonic acid (Berichte 15, 446) by treatment with alcoholic potassium sulfhydrate and introduction of gold, are dissolved in parts water. To the solution are added 15 parts formaldehyde sodium bisulphite and the solution is then heated to After cooling, the formaldehyde bisulphite compound which has formed in the solution is precipitated with methyl alcohol. It represents an almost colorless powder readily dissolving in water and having a gold content of 39 per cent. Its formula is (NH-CH -SO Na)CH -CEHSAu) scam) Ewa/mple I l 42,3 parts of 3-amino-4-auro1nercapto ben- I zene-l-sulphonic sodium (obtained from 2- nitroaniline-t-sulphonic acid by diazotization, decomposition of the dia'zo product with potassium thiocyanate, reductionof the 3-nitro l-benzene thiocyanate 1 sulphonic acid formed by such decomposition, and intro duction of gold) are dissolved in 200 parts formaldehyde sodium bisulphite and the so lution is then heated to boiling point. After cooling the formaldehyde bisulphite compound is precipitated with alcohol. The compound is readily soluble in water and has a gold content of 36 per cent. Its formula is SOHNa l Example [H 17 parts N-(a-BT-aminopyridyl)-l amino- 2-auromercaptobenzene-l sulphonic sodium (C l-L; (SO Na)- SAu) (C H N) NH SOaNa SAu NH-CHz-SOaNa.

Example I V 7 33,4 parts 8-amino-t-argentomercapto ben- V zene-1-sulphonic sodium are dissolved in parts water. After the addition of 15 parts formaldehyde sodium bisulphite the solution is heated to boiling point under stirring. After cooling the formaldehyde bisulphite compound is precipitated with alcohol. It

is readily soluble in water and has a silver content of 24: per cent. Its formula 1s SOaNa tAg Various changes may be made in the details disclosed in the foregoing specification Without departing from the invention or sacrificing the advantages thereof.

We claim 1. As new products organic metallo mercapto sulphonic compounds corresponding to the formula l X- NH-cmsomay(sodaso wherein X is an aliphatic, aromatic, or heterocyclic radical, Me a heavy metal and y either. H or a metal.

' 2. As a new product, the compound corresponding to the formula NH-CHrSOaNa being readily soluble in water and containing about 36 per cent gold.

3. The process which consists in causing a formaldehyde bisulphite to act on an amino compound of a inetallo mercapto sulphonic acid compound.

In testimony whereof We aifix our signatures.

WALTER SCHOELLER. ERICH BORGWARDT. ADOLF FELDT. 

